Table 3
Ligand bias and underlying data using ΔΔLog(Emax/EC50).
Ligand B has a weak bias (bias factor 0.8) towards pathway 2. This
information is retrieved by first calculating a
ΔLog(Emax/EC50) for Ligand B – Ligand A (the reference)
in each pathway and then a ΔΔLog(Emax/EC50) for Pathway
2 – Pathway 1.