Table 3
Ligand bias and underlying data using ΔΔLog(Emax/EC50). Ligand B has a weak bias (bias factor 0.8) towards pathway 2. This information is retrieved by first calculating a ΔLog(Emax/EC50) for Ligand B – Ligand A (the reference) in each pathway and then a ΔΔLog(Emax/EC50) for Pathway 2 – Pathway 1.