loading page

Decreasing Blood Wastage During Ex Vivo Lung Perfusion Recovery Through Utilization of Thermal Control Technology
  • +3
  • Blaine Johnson,
  • Jamie Bucio,
  • Christopher Salerno,
  • Valluvan Jeevanandam,
  • Tae Song,
  • Geoffrey Wool
Blaine Johnson
UChicago Medicine Perfusion Services

Corresponding Author:[email protected]

Author Profile
Jamie Bucio
University of Chicago Department of Surgery
Author Profile
Christopher Salerno
University of Chicago Department of Surgery
Author Profile
Valluvan Jeevanandam
University of Chicago Department of Surgery
Author Profile
Tae Song
University of Chicago Department of Surgery
Author Profile
Geoffrey Wool
University of Chicago Department of Pathology
Author Profile

Abstract

Background The Organ Care System (OCS) is a revolutionary ex vivo organ perfusion technology that can potentially expand the organ retrieval range. The OCS Lung device uses packed red blood cells (pRBC) with a proprietary solution. We report the ability to reduce blood waste during this procedure by using a thermal packaging solution in conjunction with the OCS platform. Methods We retrospectively reviewed all OCS Lung recoveries performed by our recovery team, using packed red blood cells (pRBC) from May 2019 to January 2021. Initially, units were stored using passive refrigeration with the Performance cooler at a temperature range of 1 to 6 °C for 4 hours. Subsequently, thermal control technology with the ProMed cooler was utilized to maintain the same temperature range for 72 hours. Results Twenty-three recoveries were initiated with 63 pRBC. The Performance cooler was used for eight while the ProMed cooler for thirteen. 37.5% of pRBC transported with the Performance cooler was used within the validated time range, while 25.0% were used beyond the validated time range based on clinical judgment. In addition, 37.5% of pRBC transported with the Performance cooler were returned to the institution after canceled recoveries with an estimated loss of $1,800; the ProMed cooler had no wastage. Conclusions This study showed that using an advanced thermal packaging solution facilitates proper storage of pRBC and represents an advancement for extended donor lung preservation. The elimination of blood wastage in this initial study portends ongoing benefits for the limited blood supply and reduced cost.
30 Sep 2022Submitted to Journal of Cardiac Surgery
30 Sep 2022Assigned to Editor
30 Sep 2022Submission Checks Completed
02 Oct 2022Reviewer(s) Assigned
27 Oct 2022Review(s) Completed, Editorial Evaluation Pending
29 Oct 2022Editorial Decision: Accept
Dec 2022Published in Journal of Cardiac Surgery volume 37 issue 12 on pages 5011-5018. 10.1111/jocs.17147