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Coexistence of anti-MDA5 and anti-PL-7 in a patient with dermatomyositis: a case report
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  • Hongyan Fu,
  • Shaofeng Sun,
  • Hong Zhang,
  • Shuhong Chi,
  • Weirong Ma,
  • Guilan Yang,
  • juan chen
Hongyan Fu
General Hospital of Ningxia Medical University
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Shaofeng Sun
General Hospital of Ningxia Medical University
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Hong Zhang
General Hospital of Ningxia Medical University
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Shuhong Chi
General Hospital of Ningxia Medical University
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Weirong Ma
General Hospital of Ningxia Medical University
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Guilan Yang
General Hospital of Ningxia Medical University
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juan chen
General Hospital of Ningxia Medical University
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Abstract

Anti-melanoma differentiation-associated gene 5 (anti-MDA5) and anti-threonyl-tRNA synthetase (anti-PL-7) are myositis-specific autoantibodies, associated with rapidly progressive interstitial lung disease (RP-ILD). A 41-year-old woman presented productive cough, dyspnea, and muscle pain. Anti-MDA5 and anti-PL-7 were double-positive. The patient was diagnosed with dermatomyositis-associated ILD, and responded successfully to glucocorticoids and immunosuppressants.
22 Jun 2022Submitted to Clinical Case Reports
23 Jun 2022Assigned to Editor
23 Jun 2022Submission Checks Completed
04 Jul 2022Reviewer(s) Assigned