Reverse remodeling in new onset heart failure and its affection on the
right side parameters.
Abstract
Background Patient with new onset heart failure showed improvement in
their EF and strain pattern along with improvement in cardiac biomarkers
followed intervention procedures or device implantation and medical
treatment. However right side changes are affected by these changes as
well which needed further studies. Methods Hundred patients were
included in a period starting from 2018 to 2020 and their follow up
after 3-6 months :All patients underwent full assessment including
Minnesota questionnaire of heart failure ,examination and
echocardiography with focusing on global longitudinal ,circumferential
strain ,right side areas and fractional area changes. Troponin I was
evaluated at admission and follow up. Results There was significant
change between patients at admission and follow up in Minnesta Q
questionnaire from19.1±11.6 to 13.8 ±10.4 with P value (0.001) ,and
change in troponin I 1.84.9 to 0.1 0.3 with P value <0.001.The
Ejection fraction by 2D Simpson method showed statistically significant
change from 30.6±8.5 to 41.9±14.0 with P value < 0.001,
Moreover ESV index showed a significant decrease from 50.5±21.1 to
37.5±23.2 with P value of 0.017. Global longitudinal strain showed
significant increase from 5.9±3.5 to 7.5 ±3.8with P value 0.024. The
right side dimensions of end-systolic showed a significant increase from
9.8±4.5 to 8.2 ±3.4 with P value 0.008 .FAC showed a significant
increase from a mean of 41.7±10.7 to 45.4 ±8.8 with P value of 0.008 .
Conclusion: Significant changes affected the cardiac volumes parameters
in reverse remodeled followed medical treatment and/ or
revascularization affecting both left and right side parameters..