Abstract
Maternal oxygen (O2) inhalation therapy is widely used for intrauterine
fetal resuscitation. However, the research results were inconsistent in
the effects of maternal O2 administration on fetal oxygenation. There
were only four randomized controlled trials (RCTs) of O2 inhalation
during labor showed that O2 inhalation therapy did not improve the fetal
acid-base metabolism state or even increased the risk of fetal acidosis.
Several studies showed that O2 inhalation therapy triggered
maternal-fetal oxidative stress, and several studies found
hyperoxia-induced vasoconstriction. This article reviewed the
controversy of maternal O2 administration on mother and fetus during
labor.